Edit |   |
---|---|
Antigenic Specificity | MAN1B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAN1B1 antibody detects endogenous levels of total MAN1B1. Description: MAN1B1 Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1, 2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC).Function: Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1, 2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.Simil |
Immunogen | Immunogen: A synthesized peptide derived from human MAN1B1 Subcellular Location: Endoplasmic Reticulum Membrane; Single-Pass Type II Membrane Protein. Tissue Specificity: Widely expressed. |
Other Names | [Alpha 1 2 mannosidase; Endoplasmic reticulum alpha mannosidase 1; Endoplasmic reticulum mannosyl oligosaccharide 1 2 alpha mannosidase 1; Endoplasmic reticulum mannosyl oligosaccharide 1 2 alpha mannosidase; ER alpha 1 2 mannosidase; Man9GlcNAc2 specific processing alpha mannosidase; MANA ER; Mannosidase alpha class 1B member 1] |
Gene, Accession # | [MAN1B1], Gene ID: 11253, NCBI: NP_057303.2, UniProt: Q9UKM7 |
Catalog # | MBS9600314 |
Price | $240, $280 |
Order / More Info | MAN1B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |