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Antigenic Specificity | PHF21A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 461-680 of human PHF21A (NP 001095272.1). |
Other Names | [BHC80; BM-006] |
Gene, Accession # | [PHF21A], Gene ID: 51317, NCBI: NP_001095272.1, UniProt: Q96BD5 |
Catalog # | MBS8546025 |
Price | $280 |
Order / More Info | PHF21A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |