MECA-79 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-MECA-79 antibody, protein, ELISA kits.
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| Antigenic Specificity | MECA-79 |
| Clone | [MECA-79] |
| Host Species | Rat |
| Reactive Species | human, mouse, rat |
| Isotype | IgM, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissu |
| Immunogen | Immunogen: Mouse lymph node stromal cells |
| Other Names | [MECA-79; Peripheral Node Addressin (PNAd)] |
| Gene, Accession # | [MECA-79] |
| Catalog # | MBS4381526 |
| Price | $190, $340, $340 |
| Order / More Info | MECA-79 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bistrup, A., et al. 2004. Am. J. Pathol. 164: 1635-164 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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