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Antigenic Specificity | Human CEACAM-1 |
Clone | [mouse IgG1 kappa, C5-1X] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-human CEACAM-1 (C5-1X) interacts solely with human CEACAM-1 and shows no cross-reactivity with other CEACAMs expressed in human or other species. C5-1X binds to the A1-B-Domain. Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, it forms noncovalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist. |
Immunogen | Immunogen: Recombinant human sCEACAM-1/Fc lacking the N-domain. Preparation: Monoclonal antibodies were produced with the help of NS1/0 mice using recombinant human soluble CEACAM-1-Fc lacking the N-domain (produced in HEK293 cells) as the immunizing antigen. |
Other Names | [Human CEACAM-1 (#C5-1X); Carcinoembryonic antigen-related cell adhesion molecule 1], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1] |
Gene, Accession # | [CEACAM-1], Gene ID: 634, NCBI: NP_001192273.1, UniProt: P13688 |
Catalog # | MBS690561 |
Price | $365 |
Order / More Info | Human CEACAM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Muturi HT et al, PLOS/one Vol 8, Issue 9 (2013) 2. Klaile E et al, Respiratory Research 14 (2013) 3. Waggener and Ergun, Exp Cell Res 261 (2000) 4. Barnett et al, J Cell Biol 108 (1989) 5. Hinoda et al, Proc Natl Acad Sci 85 (1998) 6. Muller et al, Blood 105 (2006) 7. Kilic et al, Blood 110 (2007) 8. Zengin et al, Development 133 (2006) 9. Oliveira-Ferrer et al, Cancer Res 64 (2004); |