Human CEACAM-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CEACAM-1
Clone[mouse IgG1 kappa, C5-1X]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: Anti-human CEACAM-1 (C5-1X) interacts solely with human CEACAM-1 and shows no cross-reactivity with other CEACAMs expressed in human or other species. C5-1X binds to the A1-B-Domain. Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, it forms noncovalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
ImmunogenImmunogen: Recombinant human sCEACAM-1/Fc lacking the N-domain. Preparation: Monoclonal antibodies were produced with the help of NS1/0 mice using recombinant human soluble CEACAM-1-Fc lacking the N-domain (produced in HEK293 cells) as the immunizing antigen.
Other Names[Human CEACAM-1 (#C5-1X); Carcinoembryonic antigen-related cell adhesion molecule 1], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1]
Gene, Accession #[CEACAM-1], Gene ID: 634, NCBI: NP_001192273.1, UniProt: P13688
Catalog #MBS690561
Price$365
Order / More InfoHuman CEACAM-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Muturi HT et al, PLOS/one Vol 8, Issue 9 (2013) 2. Klaile E et al, Respiratory Research 14 (2013) 3. Waggener and Ergun, Exp Cell Res 261 (2000) 4. Barnett et al, J Cell Biol 108 (1989) 5. Hinoda et al, Proc Natl Acad Sci 85 (1998) 6. Muller et al, Blood 105 (2006) 7. Kilic et al, Blood 110 (2007) 8. Zengin et al, Development 133 (2006) 9. Oliveira-Ferrer et al, Cancer Res 64 (2004);
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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