RSK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRSK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionRabbit polyclonal to Human RSK2. The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed serine/threonine kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, by autophosphorylation, and by phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3). Stimulation by various growth factors leads to activation of RSK2, which is a critical downstrea
ImmunogenImmunogen: A synthetic -peptide of human RSK2
Other Names[RPS6KA3; RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2, Ribosomal protein S6 kinase alpha-3, pp90RSK2], [RPS6KA3; RPS6KA3; CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3; ISPK1; MAPKAPK1B; RSK2; S6K-alpha-3; p90-RSK 3; p90RSK3; ISPK-1; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; RSK-2]
Gene, Accession #Gene ID: 6197, NCBI: NP_004577.1, UniProt: P51812
Catalog #MBS125893
Price$275, $430
Order / More InfoRSK2 Antibody from MYBIOSOURCE INC.
Product Specific References1. Fisher, T.L. and Blenis, J. (1996) Mol Cell Biol 16, 1212-9. 2. Smith, J.A. et al. (1999) J Biol Chem 274, 2893-8. 3. Dalby, K.N. et al. (1998) J Biol Chem 273, 1496-505. 4. De Cesare, D. et al. (1998) Proc Natl Acad Sci USA 95, 12202-7. 5. Sassone-Corsi, P. et al. (1999) Science 285, 886-91. 6. Cho, Y.Y. et al. (2005) Cancer Res 65, 3596-603. 7. Yang, X. et al. (2004) Cell 117, 387-98. 8. Cho, Y.Y. et al. (2007) J Biol Chem 282, 8380-92. 9. Delaunoy, J.P. et al. (2006) Clin Genet 70, 161-6.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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