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Antigenic Specificity | Synuclein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: beta-Synuclein (Ab-136) antibody detects endogenous levels of total beta-Synuclein protein. Alpha-synuclein also known as SNCA is a protein which in humans is encoded by the SNCA gene. An alpha-synuclein fragment, known as the non-Abeta component (NAC) of Alzheimer's disease amyloid, originally found in an amyloid-enriched fraction, is shown to be a fragment of its precursor protein, NACP, by cloning of the full-length cDNA. Later, NACP turned out to be a human homologue of Torpedo synuclein. Therefore, NACP is also referred to as human alpha-synuclein. |
Immunogen | Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human beta-Synuclein around the phosphorylation site of tyrosine 136 (Q-D-Y[P]-E-P). |
Other Names | [beta-Synuclein (Ab-136)], [SNCA; SNCA; PD1; NACP; PARK1; PARK4] |
Gene, Accession # | Gene ID: 6622, NCBI: AAA98493.1 |
Catalog # | MBS417188 |
Price | $405 |
Order / More Info | Synuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | Takahashi T, et al. J Biol Chem 2003 Oct 24; 278(43): 42225-33Ahn BH, et al. J Biol Chem 2002 Apr 05; 277(14): 12334-42Negro A, et al. FASEB J 2002 Feb; 16(2): 210-2Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119. |