RRM1 (N-term), 71-100 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRRM1 (N-term), 71-100
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.38
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1. This gene encodes one of two non-identical subunits thatconstitute ribonucleoside-diphosphate reductase, an enzymeessential for the production of deoxyribonucleotides prior to DNAsynthesis in S phase of dividing cells. It is one of several geneslocated in the imprinted gene domain of 11p15.5, an importanttumor-suppressor gene region. Alterations in this region have beenassociated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, andbreast cancer. This gene may play a role in malignancie
Immunogenn/a
Other Names[Ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit; RRM1; RR1]
Gene, Accession #[RRM1], Gene ID: 6240, NCBI: NP_001024.1, UniProt: P23921
Catalog #MBS9211875
Price$165, $370
Order / More InfoRRM1 (N-term), 71-100 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesUcisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Vinolas, N., et al. Lung Cancer (2010) In press : Niida, H., et al. Genes Dev. 24(4):333-338(2010) Dong, S., et al. J Hematol Oncol 3, 10 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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