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Antigenic Specificity | CD36 (Platelet & Microvessel Marker) |
Clone | [GPIIIb/654] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4 |
Immunogen | Immunogen: Recombinant human GPIIIb protein |
Other Names | [Adipocyte membrane protein; CHDS7; Collagen receptor, platelet; fatty acid translocase (FAT); Fatty acid transport protein; glycoprotein iiib (GP IIIb); PAS IV; PAS-4; pas4 protein; platelet collagen receptor; Platelet glycoprotein 4; scarb3; Scavenger receptor class B member 3; thrombospondin receptor], [CD36; CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; GP3B; GP4; FAT; GPIIIB; GPIV] |
Gene, Accession # | [CD36], Gene ID: 948, NCBI: NP_000063.2, UniProt: P16671 |
Catalog # | MBS439433 |
Price | $190, $340, $340 |
Order / More Info | CD36 (Platelet & Microvessel Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kishimoto T. et al., eds. Leukocyte Typing VI, p636-643 and p1136-1137, Garland Publishing, Inc, New York and London, 1997. Greenwalt DE Ikeda H,Tandon NN,Jamieson GA Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine. Blood 1992 80:1105 Savill J, et al. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest. 1992;90(4):1513-1522. Stomski FC et. al. Experimental Cell Research, 1992, 198(1):85-92. Biggs BA et. al. Journal of Experimental Medicine, 1990, 171(6):1883-1892 |