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Antigenic Specificity | CD90 / Thy1 (Stromal / Mesenchymal Marker) |
Clone | [AF-9] |
Host Species | Mouse |
Reactive Species | human, cow |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. |
Immunogen | Immunogen: Human T-lymphoma cells |
Other Names | [CD90; Theta antigen; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1.2; Thy-1 antigen; Thy-1 membrane glycoprotein; Thy1; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta], [THY1; THY1; CD90; CDw90] |
Gene, Accession # | [THY1], Gene ID: 7070, NCBI: NP_001298089.1, UniProt: P04216 |
Catalog # | MBS439589 |
Price | $190, $340, $340 |
Order / More Info | CD90 / Thy1 (Stromal / Mesenchymal Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Beissert S et al. Impaired cutaneous immune responses in Thy-1-deficient mice. J Immunol 1998, 161(10):5296-302 Williams, A.F., and J. Gagnon. 1982. Neuronal cell Thy-1 glycoprotein: Homology with immunoglobulin. Science 216: 696 - 703 Fujita N et al. Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp Cell Res 1997, 232(2):400-406 Kroczek, R.A., K.C. Gunter, R.N. Germain, and E.M. Shevach. 1986. Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322: 181 - 184 |