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Antigenic Specificity | ATF-2 (Phospho-Ser472) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472. Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 472 (A-L-S(p)-Q-I) derived from Human ATF-2. |
Other Names | [Activating 2; ATF2; cAMP response element binding protein CRE-BP1; CREB2; HB16] |
Gene, Accession # | [ATF-2], Gene ID: 1386, NCBI: NP_001243019.1, UniProt: P15336 |
Catalog # | MBS9402005 |
Price | $200, $255 |
Order / More Info | ATF-2 (Phospho-Ser472) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |