ASIC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASIC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatantigen affinity purified
Size0.05 mL
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionRecognizes isoforms ASIC1a and ASIC1b. ASIC1 is a member of a family of Na+ channels that are activated by external protons. The family includes another three members ASIC2, ASIC3 and ASIC4. The ASICs are in fact part of a larger superfamily termed epithelial Na+ channels (EnaC) and share with it the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N and C termini. There are two recognized splice variants of the ASIC1 gene that differ on their N-termini, ASIC1a and ASIC1b that have different tissue distributions and functions. The ASIC1 responds to a decrease in extracellular pH with an inward cation current that is quickly inactivated despite the continuous presence of pro
ImmunogenImmunogen: Peptide CQKEAKRSSADKGVALSLDD corresponding to residues 469-488 of rat ASIC1 (accession number P55926).
Other Names[acid-sensing ion channel 1 isoform b; Acid-sensing ion channel 1; acid-sensing ion channel 1; acid sensing ion channel subunit 1; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2]
Gene, Accession #[ASIC1], Gene ID: 41, UniProt: P78348
Catalog #MBS4159172
Price$725
Order / More InfoASIC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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