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Antigenic Specificity | ASIC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes isoforms ASIC1a and ASIC1b. ASIC1 is a member of a family of Na+ channels that are activated by external protons. The family includes another three members ASIC2, ASIC3 and ASIC4. The ASICs are in fact part of a larger superfamily termed epithelial Na+ channels (EnaC) and share with it the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N and C termini. There are two recognized splice variants of the ASIC1 gene that differ on their N-termini, ASIC1a and ASIC1b that have different tissue distributions and functions. The ASIC1 responds to a decrease in extracellular pH with an inward cation current that is quickly inactivated despite the continuous presence of pro |
Immunogen | Immunogen: Peptide CQKEAKRSSADKGVALSLDD corresponding to residues 469-488 of rat ASIC1 (accession number P55926). |
Other Names | [acid-sensing ion channel 1 isoform b; Acid-sensing ion channel 1; acid-sensing ion channel 1; acid sensing ion channel subunit 1; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2] |
Gene, Accession # | [ASIC1], Gene ID: 41, UniProt: P78348 |
Catalog # | MBS4159172 |
Price | $725 |
Order / More Info | ASIC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |