G6PD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | G6PD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Western blot analysis of extracts of various cell lines, using G6PD antibody. Immunohistochemistry of paraffin-embedded human esophageal cancer using G6PD antibody at dilution of 1:100 (400x lens). Glucose-6-phosphate dehydrogenase (G6PD) catalyses the first and rate-limiting step of the pentose phosphate pathway (1). The NADPH generated from this reaction is essential to protect cells from oxidative stress (1). Recent studies have shown that p53 interacts with G6PD and inhibits its activity, therefore suppressing glucose consumption through the pentose phosphate pathway (2). In cancer cells with p53 mutations, the increased glucose consumption is directed towards increased biosynthesis, which is critical for cancer cell prolif |
| Immunogen | Immunogen: Recombinant protein of human G6PD |
| Other Names | [G6pd; Glucose-6-phosphate 1-dehydrogenase; GI11107 gene product from transcript GI11107-RA], [DmojG6pd; G6pd; DmojGI11107; dmoj_GLEANR_11020; G6pd; GI11107] |
| Gene, Accession # | [G6PD], Gene ID: 6585954, NCBI: XP_002011578.1 |
| Catalog # | MBS419686 |
| Price | $385 |
| Order / More Info | G6PD Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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