Phospho-L-plastin (Tyr300) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-L-plastin (Tyr300)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-L-plastin (Tyr300) Antibody detects endogenous levels of L-plastin only when phosphorylated at Tyr300. Description: Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403).Post Translational Modifications: Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections.Subunit Structure: Monomer. Interacts with AIF1 (By similarity). Interact
ImmunogenImmunogen: A synthesized peptide derived from human L-plastin around the phosphorylation site of Tyr300. Tissue Specificity: Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.
Other Names[CP64; L plastin; L-plastin; Larval cuticle protein 1; LC64P; LCP-1; LCP1; Lplastin; Lymphocyte cytosolic protein 1; Plastin 2; Plastin-2; PLS2; PLSL_HUMAN]
Gene, Accession #[LPL], Gene ID: 3936, NCBI: EAX08758.1, UniProt: P13796
Catalog #MBS9610586
Price$225, $280, $340
Order / More InfoPhospho-L-plastin (Tyr300) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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