AR (Nonphospho-specific) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AR (Nonphospho-specific) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse, dog |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~110 kDa of human AR protein. It also reacts with mouse and rat. The other species are not tested. The androgen receptor (AR), a member of nuclear receptor family, is essential for the growth of prostate cancer cells. The phosphorylation of AR is induced by growth factors and elevated in hormone-refractory prostate tumors. It's been reported the signal pathway of the PI3K/AKT, Src to be responsible for phosphorylation of AR at Ser213/210 and Ser81. The abnormal activation of AR is observed in many diseases, such as prostate cancer. |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding the epitope -EASGA- without phosphorylation. This sequence is identical among human, rat, mouse, dog. |
| Other Names | [Rabbit AR (Paired 210); Androgen Receptor; Dihydrotestosterone Receptor], [AR; AR; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; DHTR; NR3C4] |
| Gene, Accession # | Gene ID: 367, UniProt: P10275 |
| Catalog # | MBS462011 |
| Price | $285 |
| Order / More Info | AR (Nonphospho-specific) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yasumasa Ikeda, et al (2005), Androgen Receptor Gene Knockout Male Mice Exhibit Impaired Cardiac Growth and Exacerbation of Angiotensin II-induced Cardiac Fibrosis. J. Biol. Chem., Vol. 280, Issue 33, 29661-29666. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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