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Antigenic Specificity | Human Akt (PKB) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human Akt/PKB. Akt, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: Akt1 (PKBbeta), Akt2 (PKBbeta) and Akt3 (PKBgamma) with Akt2 and Akt3 being approximately 82% identical with the Akt1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy-terminal regulatory domain. Atk is a downstream target of phosphatidylinositol 3-kinase (PI-3K) activation through the phosphorylation of Atk at two residues following the interaction of 3-phosphorylated phosphoinositides, such as PtdIns(3, 4) P2 and PtdIns (3, 4, 5) P3, via PH domains. Atk has been shown to play a role in such metabolic processes as glucose transport, glycogen s |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [Akt] |
Catalog # | MBS4152635 |
Price | $445 |
Order / More Info | Human Akt (PKB) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |