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Antigenic Specificity | APOBEC3H |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APOBEC3H antibody detects endogenous levels of total APOBEC3H. Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and-independent mechanisms. The A3H-var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism th |
Immunogen | Immunogen: A synthesized peptide derived from human APOBEC3H Subcellular Location: Nucleus. Cytoplasm. Note: Mostly nuclear. Tissue Specificity: Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung, testis, ovary, fetal liver and skin. |
Other Names | [A3H; APOBEC related protein 10; APOBEC3H; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3H; ARP 10; DNA dC-> dU-editing enzyme APOBEC-3H] |
Gene, Accession # | [APOBEC3H], Gene ID: 164668, NCBI: NP_001159474.2, UniProt: Q6NTF7 |
Catalog # | MBS9609762 |
Price | $240, $280 |
Order / More Info | APOBEC3H Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |