Human CD11c Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD11c
Clone[BU15]
Host SpeciesMouse
Reactive Speciescynomolgus monkey
IsotypeIgG1
Formatunconjugated
Size0.2 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsImmunohistology Frozen*, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
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DescriptionMouse anti Human CD11c antibody, clone Bu15 recognizes the integrin alphax subunit (ITGAX), a 150kD glycoprotein also known as CD11 antigen-like family member C or Leu M5, CD11c is expressed by macrophages, monocytes, NK cells and most dendritic cells (Kohrgruber et al. 1999). CD11c is also expressed at a lower level by granulocytes. CD11c forms a heterodimeric integral membrane protein with the integrin beta 2 chain to form the leukocyte specific integrin 'inactivated-C3b receptor 4'. CD11c interacts with a number of ligands including the G-P-R sequence in fibrinogen, ICAM-1 (Frick et al. 2005), iC3b (Sadhu et al. 2007) and Junctional adhesion molecule-like (Bazzoni et al. 2011). CD11c is involved in cell-cell interactions during the infla
Immunogenn/a
Other Names[integrin alpha-X isoform 2; Integrin alpha-X; integrin alpha-X; CD11 antigen-like family member C; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; integrin, alpha X (complement component 3 receptor 4 subunit); CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c], [ITGAX; ITGAX; CD11C; SLEB6; CD11C]
Gene, Accession #[CD11c], Gene ID: 3687, NCBI: NP_000878.2, UniProt: P20702
Catalog #MBS212480
Price$430
Order / More InfoHuman CD11c Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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