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Antigenic Specificity | Human AMYLOID PRECURSOR PROTEIN (KPI DOMAIN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | monkey |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP)*, Immunohistology Paraffin*, Western Blot (WB)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human Amyloid Precursor Protein antibody recognizes an epitope in the Kunitz protease inhibitor (KPI) domain of human amyloid precursor protein (APP). Only the APP-751 and APP-770 isoforms contain a KPI domain, it being absent from the APP-695 isoform that is most abundant in neuronal tissue. However, there is evidence that suggests KPI containing isoforms may be important in the pathogenesis of Alzheimer disease. Rabbit anti Human Amyloid Precursor Protein antibody recognizes a band of ~115kDa in NTera2/DI cell lysates using western blotting under reducing conditions. |
Immunogen | Histology Positive Control Tissue: Alzheimer's disease brain. Antiserum Preparation: Antisera to human APP were raised by repeated immunisations of rabbits with highly purified antigen. Target Species: Human |
Other Names | [amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; alzheimer disease amyloid protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II], [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)] |
Gene, Accession # | Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067 |
Catalog # | MBS222453 |
Price | $550 |
Order / More Info | Human AMYLOID PRECURSOR PROTEIN (KPI DOMAIN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |