GSK-3b pS133 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GSK-3b pS133 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GSK-3b pS133 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, cow, sheep, porcine |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mg, 0.2 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GSK-3 has been identified as a target of Akt that plays a role in the regulation of apoptosis in a variety of normal and transformed cell types including muscle cells, hepatocytes, neurons, and colon cancer cells. Akt-dependent phosphorylation of GSK-3 causes its inactivation, blocking downstream proapoptotic pathways, e.g., caspase and -catenin signaling. Akt-dependent regulation of GSK-3 activity contributes to the growth and hypertrophy of skeletal and cardiac muscle and inhibits apoptosis in vascular smooth muscle |
| Immunogen | Source Note: Polyclonal GSK-3 beta antibody was produced from sera of mice immunized with synthetic protein containing GSK-3 beta antigenic determinants. |
| Other Names | [Rabbit Glycogen Synthase Kinase-3b purified; Rabbit Glycogen Synthase Kinase-3beta purified; gsk3beta; gsk3-beta;; Glycogen synthase kinase], [GSK-3 beta] |
| Gene, Accession # | [GSK3b], Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
| Catalog # | MBS551060 |
| Price | $315, $445 |
| Order / More Info | GSK-3b pS133 Antibody from MYBIOSOURCE INC. |
| Product Specific References | • age-associated differences in activation of akt/gsk-3β signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart.J Gerontol A Biol Sci Med Sci, Jun 2010; 65A: 611 - 619. • troglitazone ameliorates high glucose-induced emt and dysfunction of sglts through pi3k/akt, gsk-3β, snail1, and β-catenin in renal proximal tubule cells.Am J Physiol Renal Physiol, May 2010; 298: F1263 - F1275. • hydrogen sulfide protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by preventing gsk-3β-dependent opening of mptp.Am J Physiol Heart Circ Physiol, May 2010; 298: H1310 - H1319. • troglitazone ameliorates high glucose-induced emt and dysfunction of sglts through pi3k/akt, gsk-3β, snail1, and β-catenin in renal proximal tubule cells.Am J Physiol Renal Physiol, May 2010; 298: F1263 - F1275. • extracellular ubiquitin inhibits β-ar-stimulated apoptosis in cardiac myocytes: role of gsk-3β and mitochondrial pathways.Cardiovasc Res, Apr 2010; 86: 20 - 28. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies