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Antigenic Specificity | CD68 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD68 antibody detects endogenous levels of total CD68. Function: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue-and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.Post-translational Modifications: N-and O-glycosylated.Similarity: Belongs to the LAMP family. |
Immunogen | Immunogen: A synthesized peptide derived from human CD68 Subcellular Location: Cell Membrane and Endosome Membrane. Lysosome Membrane. Tissue Specificity: Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Do |
Other Names | [CD 68; CD68; CD68 antigen; CD68 molecule; CD68_HUMAN; DKFZp686M18236; gp11; Gp110; LAMP4; Macrophage antigen CD68 (microsialin); MACROPHAGE ANTIGEN CD68; Macrosialin; SCARD1; Scavenger receptor class D member 1] |
Gene, Accession # | [CD68], Gene ID: 968, NCBI: NP_001035148.1, UniProt: P34810 |
Catalog # | MBS9608127 |
Price | $240, $280 |
Order / More Info | CD68 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |