Cellular Apoptosis Susceptibility (N-term), 55-84 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cellular Apoptosis Susceptibility (N-term), 55-84 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine, zebrafish) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human Cellular Apoptosis Susceptibility. Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 |
| Immunogen | n/a |
| Other Names | [Exportin-2; Exp2; Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter; CSE1L; CAS; XPO2] |
| Gene, Accession # | [CSE1L], Gene ID: 1434, NCBI: NP_001243064.1, UniProt: P55060 |
| Catalog # | MBS9201059 |
| Price | $165, $370 |
| Order / More Info | Cellular Apoptosis Susceptibility (N-term), 55-84 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Goldberg, G.S., et al., J. Biol. Chem. 278(47):46533-46540 (2003). Behrens, P., et al., Apoptosis 8(1):39-44 (2003). Jiang, M.C., et al., Biochem. Biophys. Res. Commun. 294(4):900-905 (2002). Wellmann, A., et al., Int. J. Mol. Med. 7(5):489-494 (2001). Brinkmann, U., et al., Genomics 58(1):41-49 (1999). |
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MYBIOSOURCE INC.
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