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Antigenic Specificity | Human EGF |
Clone | [S-146] |
Host Species | Mouse |
Reactive Species | human. other species not tested. does not cross react with other human cytokines tested such as IL-1beta, IL-8, MCAF, TGF-beta and SAA. |
Isotype | IgG1,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reactive with natural and recombinant human EGF. Does not cross react with other human cytokines tested such as IL-1 beta, IL-8, MCAF and TGF-beta. Epidermal growth factor (EGF), along with its receptor EGFR, plays an important role in cell proliferation, differentiation and survival. The binding of EGF to EGFR triggers the intrinsic tyrosine kinase activity of EGFR, activates signalling molecules and stimulates the synthesis of proteins and DNAs. EGF is crucial for maintaining mucosal lining in gastrointestinal duct and for healing of oral and gastroesophageal ulcers. EGF signalling is needed for cancer growth. Monoclonal antibodies that block EGFR have been applied for lung cancer and colon cancer treatment. |
Immunogen | Immunogen: Purified recombinant human EGF, 6kDa, 53 amino acid residues. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. |
Other Names | [Epidermal Growth Factor (EGF); Mouse to human epidermal growth factor (EGF)], [epidermal growth factor/ EGF] |
Gene, Accession # | [EGF], NCBI: AAB32226.1 |
Catalog # | MBS592025 |
Price | $490 |
Order / More Info | Human EGF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |