PELI2 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPELI2 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionE3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PELI2
Other Names[E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin-protein ligase pellino homolog 2; pellino E3 ubiquitin protein ligase family member 2]
Gene, Accession #[PELI2], Gene ID: 57161, NCBI: NP_067078.1, UniProt: Q9HAT8
Catalog #MBS3222857
Price$335
Order / More InfoPELI2 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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