Edit |   |
---|---|
Antigenic Specificity | CDK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons. |
Immunogen | Immunogen: CDK5 antibody was raised in Rabbit using a His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells as the immunogen |
Other Names | [Rabbit CDK5; CDK5; CDK5; CDK5; cyclin-dependent kinase 5; BOS_4735; Cdk5-PA; cell division protein kinase 5; CG8203-PA; CR6 protein kinase; Crk6; cyclin-dependent protein kinase 5; DmCdk5; Dmel_CG8203; neuronal cyclin-dependent kinase 5; NV14994; PDPK; proline-directed protein kinase 33 kDa subunit; protein kinase CDK5 splicing; pssalre; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit] |
Gene, Accession # | [CDK5], Gene ID: 1020, NCBI: CAG33322.1, UniProt: Q6IAW3 |
Catalog # | MBS5310045 |
Price | $375 |
Order / More Info | CDK5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |