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Antigenic Specificity | ARP2/3 Subunit 1B/ARPC1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. It is mapped to 7q22.1. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that |
Immunogen | Immunogen: E Coli-derived human ARP2/3 subunit 1B/ARPC1B recombinant protein (Position: Q293-K372). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P). |
Other Names | [Actin-related protein 2/3 complex subunit 1B; actin related protein 2/3 complex subunit 1B; Actin-related protein 2/3 complex subunit 1B; Arp2/3 complex 41 kDa subunit; p41-ARC; ARPC1B; ARC41] |
Gene, Accession # | [ARPC1B], Gene ID: 10095, NCBI: NP_005711.1, UniProt: O15143 |
Catalog # | MBS1752532 |
Price | $315 |
Order / More Info | ARP2/3 Subunit 1B/ARPC1B Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kahr, W. H. A., Pluthero, F. G., Elkadri, A., Warner, N., Drobac, M., Chen, C. H., Lo, R. W., Li, L., Li, R., Li, Q., Thoeni, C., Pan, J., and 10 others. Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. Nature Commun. 8: 14816, 2017. Note: Electronic Article. 2. Laurila, E., Savinainen, K., Kuuselo, R., Karhu, R., Kallioniemi, A. Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Genes Chromosomes Cancer 48: 330-339, 2009. |