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Antigenic Specificity | VWF |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for von Willebrand factor(VWF) detection. Tested with WB, IHC-P in Mouse;Rat. Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues havin |
Immunogen | Immunogen: E Coli-derived mouse VWF recombinant protein (Position: M1304-E1452). Ig Type: Rabbit IgG |
Other Names | [von Willebrand factor; Coagulation factor VIII; Coagulation factor VIII VWF; F8VWF; Factor VIII related antigen; von Willebrand antigen 2; Von Willebrand antigen II; Von Willebrand disease; VWD; VWF; VWF_HUMAN; von Willebrand factor], [Vwf; Vwf; VWD; F8VWF; AI551257; C630030D09; 6820430P06Rik; B130011O06Rik; vWF] |
Gene, Accession # | [VWF], Gene ID: 22371, NCBI: NP_035838.3, UniProt: Q8CIZ8 |
Catalog # | MBS178323 |
Price | $315 |
Order / More Info | VWF Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sadler JE (1998). Biochemistry and genetics of von Willebrand factor. Annu. Rev. Biochem. 67: 395-424. 2. Ginsburg, D., Handin, R. I., Bonthron, D. T., Donlon, T. A., Bruns, G. A. P., Latt, S. A., Orkin, S. H. Human von Willebrand factor (VWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science 228: 1401-1406, 1985. 3. Sporn, L. A., Marder, V. J., Wagner, D. D. Von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 69: 1531-1534, 1987. |