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Antigenic Specificity | Human FAP Alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (tested or 100% immunogen sequence identity). predicted monkey, mouse, rat, bovine, dog, hamster, horse, porcine, rabbit (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human FAP. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2 (PubMed:14751930, PubMed:16223769, PubMed:16480718, PubMed:16410248, PubMed:17381073, PubMed:18095711, PubMed:21288888, PubMed:24371721). Degrade also gelatin, heat-denatured type I collag |
Immunogen | Immunogen Description: FAP Alpha antibody was raised against synthetic 17 amino acid peptide from extracellular domain of human FAP. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum (94%); Marmoset, Bat, Turkey, Chicken (88%). Epitope: Extracellular domain |
Other Names | [FAP Alpha (Extracellular Domain) IHC-plus; DPPIV; FAP alpha; Fibroblast activation protein; FAPA; Seprase; Human FAP Alpha], [FAP; FAP; FAPA; SIMP; DPPIV] |
Gene, Accession # | [FAP], Gene ID: 2191, NCBI: NP_004451.2, UniProt: Q12884 |
Catalog # | MBS240133 |
Price | $530 |
Order / More Info | Human FAP Alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |