Human FAP Alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman FAP Alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (tested or 100% immunogen sequence identity). predicted monkey, mouse, rat, bovine, dog, hamster, horse, porcine, rabbit (at least 90% immunogen sequence identity)
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin)
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DescriptionSpecificity: Human FAP. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2 (PubMed:14751930, PubMed:16223769, PubMed:16480718, PubMed:16410248, PubMed:17381073, PubMed:18095711, PubMed:21288888, PubMed:24371721). Degrade also gelatin, heat-denatured type I collag
ImmunogenImmunogen Description: FAP Alpha antibody was raised against synthetic 17 amino acid peptide from extracellular domain of human FAP. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum (94%); Marmoset, Bat, Turkey, Chicken (88%). Epitope: Extracellular domain
Other Names[FAP Alpha (Extracellular Domain) IHC-plus; DPPIV; FAP alpha; Fibroblast activation protein; FAPA; Seprase; Human FAP Alpha], [FAP; FAP; FAPA; SIMP; DPPIV]
Gene, Accession #[FAP], Gene ID: 2191, NCBI: NP_004451.2, UniProt: Q12884
Catalog #MBS240133
Price$530
Order / More InfoHuman FAP Alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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