GCK Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GCK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Germinal center kinase (GCK) is the founding member of the GCK family, a group of serine/threonine kinases homologous to the yeast Ste20 kinase. GCK is activated by TNF and associated with TRAF2 (TNF receptor-associated factor 2) and MEKK1, thereby activating the SAPK/JNK pathway (1, 2). GCK does not significantly phosphorylate MEKK1, instead it enhances MEKK1 oligomerization and autophosphorylation (3). GCK binds and activates MLK3, indicating that GCK may have other effectors (3). |
| Immunogen | Immunogen: Fusion protein of human GCK Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [GCK; GK; GLK; HHF3; HK4; HKIV; HXKP; MODY2] |
| Gene, Accession # | [GCK], Gene ID: 2645, NCBI: NP_000153.1, UniProt: P35557 |
| Catalog # | MBS8527327 |
| Price | $310 |
| Order / More Info | GCK Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Pombo, C. M. et al. (1995) Nature 377, 750-754. 2. Yuasa, T. et al. (1998) J. Biol. Chem. 273, 22681-22692. 3. Chadee, D. N. et al. (2002) Mol. Cell. Biol. 22, 737-749. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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