Mouse Stk3 (C-term), 387-415 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Stk3 (C-term), 387-415 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Stk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of mouse Stk3. Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates a |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase 3; Mammalian STE20-like protein kinase 2; MST-2; STE20-like kinase MST2; Serine/threonine-protein kinase 3 36kDa subunit; MST2/N; Serine/threonine-protein kinase 3 20kDa subunit; MST2/C; Stk3; Mess1; Mst2] |
| Gene, Accession # | [Stk3], Gene ID: 56274, NCBI: NP_062609.2, UniProt: Q9JI10 |
| Catalog # | MBS9204660 |
| Price | $165, $370 |
| Order / More Info | Mouse Stk3 (C-term), 387-415 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Oh, H.J., et al. Curr. Biol. 20(5):416-422(2010) Lu, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1437-1442(2010) Song, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1431-1436(2010) Zhou, D., et al. Cancer Cell 16(5):425-438(2009) Choi, J., et al. PLoS ONE 4 (11), E8011 (2009) : |
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MYBIOSOURCE INC.
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