CREST Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CREST |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CREST antibody detects endogenous levels of CREST. Function: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recrui |
| Immunogen | Immunogen: A synthesized peptide derived from human CREST. Subcellular Location: Nucleus. Chromosome > Centromere > Kinetochore. Localizes to nuclear bodies. Co-localizes with SGOL1 at kinetochore. Tissue Specificity: Ubiquitous; with lowest levels in spleen. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (92%), Horse (100%), Sheep (83%), Rabbit (92%), Dog (100%), Chicken (100%), Xenopus (83%) |
| Other Names | [Calcium-responsive transactivator; CREST; CREST_HUMAN; KIAA0693; LP2261; MGC26711; MGC78386; sarcoma translocation gene on chromosome18like1; SS18; SS18-like protein 1; SS18L1; SSXT; synovial sarcoma translocation; synovial sarcoma translocation gene on chromosome 18-like 1; SYT homolog 1] |
| Gene, Accession # | [CREST], Gene ID: 26039, NCBI: NP_001288707.1, UniProt: O75177 |
| Catalog # | MBS9603490 |
| Price | $240, $280 |
| Order / More Info | CREST Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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