M CD31 (C-term), 508-536 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityM CD31 (C-term), 508-536
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, hamster
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of mouse CD31. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell wit
Immunogenn/a
Other Names[Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam; Pecam-1]
Gene, Accession #[Pecam1], Gene ID: 18613, NCBI: NP_032842.2, UniProt: Q08481
Catalog #MBS9213675
Price$165, $370
Order / More InfoM CD31 (C-term), 508-536 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDeLisser, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18616-18621(2010) Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010) Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010) Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010) Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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