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Antigenic Specificity | M CD31 (C-term), 508-536 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, hamster |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of mouse CD31. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell wit |
Immunogen | n/a |
Other Names | [Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam; Pecam-1] |
Gene, Accession # | [Pecam1], Gene ID: 18613, NCBI: NP_032842.2, UniProt: Q08481 |
Catalog # | MBS9213675 |
Price | $165, $370 |
Order / More Info | M CD31 (C-term), 508-536 Antibody from MYBIOSOURCE INC. |
Product Specific References | DeLisser, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18616-18621(2010) Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010) Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010) Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010) Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010) |