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Antigenic Specificity | ABAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ABAT protein. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnor |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human ABAT. |
Other Names | [GABAT; NPD009; GABA-AT] |
Gene, Accession # | [ABAT], Gene ID: 18, NCBI: NP_000654.2, UniProt: P80404 |
Catalog # | MBS9408979 |
Price | $255 |
Order / More Info | ABAT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |