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Antigenic Specificity | PRKCE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-independent, phospholipid-and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transp |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human PRKCE (NP 005391.1). |
Other Names | [PKCE; nPKC-epsilon] |
Gene, Accession # | [PRKCE], Gene ID: 5581, NCBI: NP_005391.1, UniProt: Q02156 |
Catalog # | MBS8544804 |
Price | $280 |
Order / More Info | PRKCE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |