HDAC11 (N-term), 1-30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHDAC11 (N-term), 1-30
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11. HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapox
Immunogenn/a
Other Names[Histone deacetylase 11; HD11; HDAC11]
Gene, Accession #[HDAC11], Gene ID: 79885, NCBI: NP_001129513.1, UniProt: Q96DB2
Catalog #MBS9206837
Price$165, $370
Order / More InfoHDAC11 (N-term), 1-30 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesVoelter-Mahlknecht S, et al., Int J Mol Med. 2005 Oct;16(4):589-98. Bradbury CA, et al., Leukemia. 2005 Oct;19(10):1751-9. Gregoretti IV, et al., J Mol Biol. 2004 Apr 16;338(1):17-31. Gao, L., et al., J. Biol. Chem. 277(28):25748-25755 (2002).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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