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Antigenic Specificity | UBE1C (C-term), 415-445 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: zebrafish, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-445 amino acids from the C-terminal region of human UBE1C. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, whic |
Immunogen | n/a |
Other Names | [NEDD8-activating enzyme E1 catalytic subunit; 632-; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme E1C; Ubiquitin-like modifier-activating enzyme 3; Ubiquitin-activating enzyme 3; UBA3; UBE1C] |
Gene, Accession # | [UBA3], Gene ID: 9039, NCBI: NP_003959.3, UniProt: Q8TBC4 |
Catalog # | MBS9211746 |
Price | $165, $370 |
Order / More Info | UBE1C (C-term), 415-445 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bohnsack, R.N., et al., J. Biol. Chem. 278(29):26823-26830 (2003). Walden, H., et al., Nature 422(6929):330-334 (2003). Gong, L., et al., J. Biol. Chem. 274(17):12036-12042 (1999). Gubin, A.N., et al., Genomics 59(2):168-177 (1999). Osaka, F., et al., Genes Dev. 12(15):2263-2268 (1998). |