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Antigenic Specificity | CD137L/4-1BBL/TNFSF9 |
Clone | [CD137L/1547] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFSF9/4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is tho |
Immunogen | Immunogen: Recombinant full-length human CD137L protein |
Other Names | [4-1BB ligand; 4-1BBL; CD137L; ILA ligand (TNF related); Ly63l; Tumor necrosis factor ligand 5A (TNLG5A); Tumor necrosis factor ligand superfamily member 9 (TNFSF9)] |
Gene, Accession # | [TNFSF9], Gene ID: 8744, NCBI: NP_003802.1, UniProt: P41273 |
Catalog # | MBS4381364 |
Price | $190, $340, $340 |
Order / More Info | CD137L/4-1BBL/TNFSF9 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zhao S, et al. Am J Surg Pathol, 2013 Feb. PMID 23095505. 2. Qian Y, et al. Med Oncol, 2015 Mar. PMID 25631633 |