DDX60 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DDX60 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: At least three isoforms of DDX60 are known to exist; this antibody will detect all three isoforms. DDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling. |
| Immunogen | Immunogen: DDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60. Buffer: DDX60 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [DDX60; Probable ATP-dependent RNA helicase DDX60; DEAD box protein 60; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60], [DDX60; DDX60] |
| Gene, Accession # | [DDX60], Gene ID: 55601, NCBI: NP_060101, UniProt: Q8IY21 |
| Catalog # | MBS153369 |
| Price | $375 |
| Order / More Info | DDX60 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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