Mouse Emilin-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Emilin-1
Clone[IgG2a/kappa, C11A8]
Host SpeciesRat
Reactive Speciesmouse
Isotypen/a
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) - Formalin
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DescriptionEmilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.
ImmunogenImmunogen: recombinant mouse Emilin-1. Preparation: Monoclonals were produced with the help of Wistar rat using recombinant murine Emilin-2 as immunizing antigen
Other Names[mouse Emilin-1 (#C11A8); Elastin micofibril interface-located protein 1], [Emilin1; Emilin1; gp115; AW229038; BB105748; EMILIN-1; 5830419M17Rik; Elastin microfibril interfacer 1]
Gene, Accession #Gene ID: 100952, NCBI: NP_598679.1, UniProt: Q99K41
Catalog #MBS690964
Price$365
Order / More InfoMouse Emilin-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Colombatti A et al, J Cell Biol 100:18, 1985. 3. Doliana R et al, J Biol Chem 274:16773, 1999. 4. Zanetti M et al, Mol Cell Biol 24:638, 2004 5. Zacchigna L et al, Cell 124:929, 2006 6. Danussi C et al, Mol Cell Biol 28:4026, 2008. 7. Danussi C et al, J Cell Biol, in press
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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