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Antigenic Specificity | Phospho-CDC25A(Ser75) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CDC25A(Ser75) antibody detects endogenous levels of CDC25A only when phosphorylated at Sersine 75. Description: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.Function: Tyrosine protein phosphatase which functions as a dosage-dependent i |
Immunogen | Immunogen: A synthesized peptide derived from human CDC25A around the phosphorylation site of Sersine 75 |
Other Names | [Cdc 25a; CDC25A; CDC25A2; CDC25A2 CAG isoform; Cell division cycle 25 homolog A (S. pombe); Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform b; D9Ertd393e; Dual specificity phosphatase Cdc25A; M phase inducer phosphatase 1; M-phase inducer phosphatase 1; MGC115549; MPIP1_HUMAN] |
Gene, Accession # | [CDC25A], Gene ID: 993, NCBI: NP_001780.2, UniProt: P30304 |
Catalog # | MBS9600008 |
Price | $240, $280 |
Order / More Info | Phospho-CDC25A(Ser75) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |