Human Mitochondrial intermembrane space import and assembly protein 40 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Mitochondrial intermembrane space import and assembly protein 40 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | caprylic acid ammonium sulfate precipitate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system. |
| Immunogen | Immunogen: Recombinant human Mitochondrial intermembrane space import and assembly protein 40 protein(1-142aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-98628 / sc-102436 / sc-102437 |
| Other Names | [Coiled-coil-helix-coiled-coil-helix domain-containing protein 4; CHCHD4], [CHCHD4; CHCHD4; MIA40; TIMM40; MIA40] |
| Gene, Accession # | [MIA40], Gene ID: 131474, NCBI: NP_001091972.1, UniProt: Q8N4Q1 |
| Catalog # | MBS1493063 |
| Price | $160, $235 |
| Order / More Info | Human Mitochondrial intermembrane space import and assembly protein 40 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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