RB (Phospho Ser612) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RB (Phospho Ser612) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Rb (S612) Polyclonal Antibody detects endogenous levels of Rb protein only when phosphorylated at S612. The protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Immunogen | Immunogen: Synthesized peptide derived from human Rb around the phosphorylation site of S612 |
| Other Names | [Rabbit Rb (phospho Ser612); RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110] |
| Gene, Accession # | [RB], Gene ID: 5925, NCBI: NP_000312.2, UniProt: P06400 |
| Catalog # | MBS9706625 |
| Price | $130, $220, $325 |
| Order / More Info | RB (Phospho Ser612) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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