Shank1, 469-691 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Shank1, 469-691 |
| Clone | [S22-21] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Shank1. This antibody recognizes human, mouse, and rat Shank 1. It does not react with Shank2 or 3. Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling. Recent studies suggest that disruption of glutamate receptors at the Shank-postsynaptic platform could contribute to the destruction of postsynaptic density which underlies synaptic dysfunction and loss in Alzheimer's disease. Shank1 might be relevant to human autism spectrum disorders due to its differenti |
| Immunogen | Antigen: Fusion protein corresponding to aa 469-691 (SH3/PDZ domains) of rat Shank1 (accession no. Q9WV48). This sequence is 96% homologous with human and 100% homologous with mouse Shank1. |
| Other Names | [SH3 and multiple ankyrin repeat domains protein 1; SH3 and multiple ankyrin repeat domains protein 1; SH3 and multiple ankyrin repeat domains protein 1; OTTHUMP00000174437; OTTHUMP00000174438; SSTR-interacting protein; somatostatin receptor-interacting protein; SH3 and multiple ankyrin repeat domains 1; Somatostatin receptor-interacting protein], [SHANK1; SHANK1; SSTRIP; SPANK-1; synamon] |
| Gene, Accession # | Gene ID: 50944, NCBI: NP_057232.2, UniProt: Q9Y566 |
| Catalog # | MBS190526 |
| Price | $410 |
| Order / More Info | Shank1, 469-691 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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