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Antigenic Specificity | ITGAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. |
Immunogen | Immunogen: Recombinant human Integrin alpha-M protein (46-150AA) |
Other Names | [Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion; ITGAM; CD11B; CR3A] |
Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS7048484 |
Price | $160, $235 |
Order / More Info | ITGAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |