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Antigenic Specificity | RUVBL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human RUVBL1. RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 comple |
Immunogen | Immunogen: Recombinant protein corresponding to human RUVBL1 |
Other Names | RUVBL1 (RuvB-like 1, 49kD TATA Box-binding Protein-interacting Protein, 49kD TBP-interacting Protein, TIP49a, Pontin 52, Nuclear Matrix Protein 238, NMP 238, 54kD Erythrocyte Cytosolic Protein, TIP60-associated Protein 54-alpha, TAP54-alpha, INO80 Complex |
Gene, Accession # | Gene ID: 8607, NCBI: NP_003698.1, UniProt: Q9Y265 |
Catalog # | MBS625621 |
Price | $610 |
Order / More Info | RUVBL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |