Phospho-Cdk2 (Thr160) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Cdk2 (Thr160)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); ELISA (EIA); Immunohistochemistry (IHC)
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DescriptionPolyclonal antibody to detect endogenous levels of Cdk2 (pT160) in human; mouse and rat samples. Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis; but dispensable for mitosis. Phosphorylates CTNNB1; USP37; p53/TP53; NPM1; CDK7; RB1; BRCA2; MYC; NPAT; EZH2. Interacts with cyclins A; B1; B3; D; or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis; and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation; and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus.
ImmunogenImmunogen: Synthesized peptide derived from human Cdk2 around the phosphorylation site of T160.
Other Names[Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2; CDKN2], [CDK2; CDKN2]
Gene, Accession #[Cdk2], Gene ID: 1017, NCBI: NP_001277159.1, UniProt: P24941
Catalog #MBS846139
Price$335
Order / More InfoPhospho-Cdk2 (Thr160) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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