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Antigenic Specificity | Phospho-Cdk2 (Thr160) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of Cdk2 (pT160) in human; mouse and rat samples. Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis; but dispensable for mitosis. Phosphorylates CTNNB1; USP37; p53/TP53; NPM1; CDK7; RB1; BRCA2; MYC; NPAT; EZH2. Interacts with cyclins A; B1; B3; D; or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis; and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation; and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. |
Immunogen | Immunogen: Synthesized peptide derived from human Cdk2 around the phosphorylation site of T160. |
Other Names | [Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2; CDKN2], [CDK2; CDKN2] |
Gene, Accession # | [Cdk2], Gene ID: 1017, NCBI: NP_001277159.1, UniProt: P24941 |
Catalog # | MBS846139 |
Price | $335 |
Order / More Info | Phospho-Cdk2 (Thr160) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |