GADD34 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GADD34 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GADD34 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat; |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Please decide the specificity by homology. GADD34, also named PPP1R15A, belongs to the PPP1R15 family. GADD34 can be triggered as a direct target of activating transcription factor4 (ATF4) under ER stress, it plays a pivotal role in the recovery of cells from shut-down of translation induced by ER stress. It recruits the serine/threonine-protein phosphatase (PP1) to dephosphorylate the translation initiation factor eIF2alpha, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. GADD34 down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 via PP1. It may also promote apoptosis by inducing TP53 phosphorylation on ' |
| Immunogen | Immunogen: Protein phosphatase 1, regulatory (inhibitor) subunit 15A. Calculated MW: 100 kDa |
| Other Names | [GADD34, growth arrest and DNA damage-inducible protein 34, PPP1R15A], [Gadd34; CG3825; dGADD34; Dm-GADD34; DmelCG3825; dPPP1R15; gadd34; GADD34] |
| Gene, Accession # | [GADD34], Gene ID: 37820, NCBI: NP_611863.1, UniProt: O75807 |
| Catalog # | MBS769525 |
| Price | $290 |
| Order / More Info | GADD34 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies