Edit |   |
---|---|
Antigenic Specificity | TRI56 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of TRI56 protein. TRIM56 (Tripartite Motif Containing 56) is a Protein Coding gene. Among its related pathways are Cytosolic sensors of pathogen-associated DNA and Innate Immune System. GO annotations related to this gene include poly(A) RNA binding and ubiquitin-protein transferase activity. An important paralog of this gene is TRIM3. E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity (PubMed: 21289118). In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to Lys-63-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (By similarity). Independently of its E3 ub |
Immunogen | Immunogen: Synthesized peptide derived from part region of human TRI56 protein at amino acid sequence of 121-170 |
Other Names | [Rabbit TRI56; E3 ubiquitin-protein ligase TRIM56; RING finger protein 109; RING-type E3 ubiquitin transferase TRIM56; Tripartite motif-containing protein 56] |
Gene, Accession # | [TRI56], Gene ID: 81844, NCBI: NP_112223, UniProt: Q9BRZ2 |
Catalog # | MBS9711278 |
Price | $130, $220, $325 |
Order / More Info | TRI56 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |