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Antigenic Specificity | ING2 |
Clone | [AT39E5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1b,k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides. |
Immunogen | Immunogen: Recombinant human ING2 (1-280aa) purified from E. coli |
Other Names | [inhibitor of growth protein 2; ING1L; P33ing2], [ING2; ING2; ING1L; p33ING2; ING1L; ING1Lp] |
Gene, Accession # | [ING2], Gene ID: 3622, NCBI: NP_001555, UniProt: Q9H160 |
Catalog # | MBS200295 |
Price | $240, $315 |
Order / More Info | ING2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Entrez Gene: ING2 inhibitor of growth family, member 2; Shimada Y., et al. (1999) Cytogenet Cell Genet 83 (3-4): 232-5; Nagashima M., et al. (2001) Proc. Natl. Acad. Sci. U.S.A. 98: 9671-9676; Gozani O., et al. (2003) Cell 114: 99-111; |