ING2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityING2
Clone[AT39E5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1b,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.
ImmunogenImmunogen: Recombinant human ING2 (1-280aa) purified from E. coli
Other Names[inhibitor of growth protein 2; ING1L; P33ing2], [ING2; ING2; ING1L; p33ING2; ING1L; ING1Lp]
Gene, Accession #[ING2], Gene ID: 3622, NCBI: NP_001555, UniProt: Q9H160
Catalog #MBS200295
Price$240, $315
Order / More InfoING2 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesEntrez Gene: ING2 inhibitor of growth family, member 2; Shimada Y., et al. (1999) Cytogenet Cell Genet 83 (3-4): 232-5; Nagashima M., et al. (2001) Proc. Natl. Acad. Sci. U.S.A. 98: 9671-9676; Gozani O., et al. (2003) Cell 114: 99-111;
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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