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Antigenic Specificity | Human Protein kinase C epsilon type |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional trans |
Immunogen | Immunogen: Recombinant human Protein kinase C epsilon type protein(488-737aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-214 |
Other Names | [nPKC-epsilon; PRKCE; PKCE], [PRKCE; PRKCE; PKCE; nPKC-epsilon; PKCE] |
Gene, Accession # | [PRKCE], Gene ID: 5581, NCBI: NP_005391.1, UniProt: Q02156 |
Catalog # | MBS1491958 |
Price | $120, $160 |
Order / More Info | Human Protein kinase C epsilon type Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |