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Antigenic Specificity | KREMEN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members. KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodelin |
Immunogen | Immunogen: KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2. Buffer: KREMEN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [KREMEN2; KRM2; KRM2; Kremen protein 2; Dickkopf receptor 2; kringle containing transmembrane protein 2], [KREMEN2; KREMEN2; KRM2; KRM2] |
Gene, Accession # | [KREMEN2], Gene ID: 79412, NCBI: NP_757384, UniProt: Q8NCW0 |
Catalog # | MBS153545 |
Price | $375 |
Order / More Info | KREMEN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |